VetGen - The leader in veterinary genetic disease research and genetic disease detection services for purebred animals

Breeds Serviced

  • Gordon Setter
  • Olde English Sheepdog

Cerebellar Ataxia-autophagy

Cerebellar Ataxias are a heterogeneous disease group, characterized by cerebellar degeneration and dysfunction. The cerebellum is a part of the brain that is involved in coordination of movement. Degeneration of the cerebellar structures causes ataxia, which is a neurological sign of defective motor coordination that can affect gait, balance, speech and gaze.

The test offer by VetGen was developed by Dr. Natasha Olby at North Carolina State University, in collaborations with the Canine Genetic Disease Network. They identified a mutation in RAB24, a gene associated with autophagy, in Olde English Sheepdogs and Gordon Setters with autosomal recessive cerebellar ataxia.

Result types: Clear or Affected