VetGen - The leader in veterinary genetic disease research and genetic disease detection services for purebred animals

Breeds Serviced

  • French Bulldog
  • Tenterfield Terrier
  • Toy Fox Terrier

CHG-Congenital Hypothyroidism with Goiter

CHG-Congenital Hypothyroidism with Goiter in dogs is inherited as an autosomal recessive disease. As with adult onset hypothyroidism, there are a number of metabolic abnormalities seen in affected pups, but there are also additional symptoms such as delayed development, small stature, difficulty nursing and other symptoms collectively referred to as cretinism. The cause of this disease in dogs can be attributed to mutations in the Thyroid Peroxidase gene discovered by researchers at Michigan State University and elsewhere.

CHG is an autosomal recessive disorder.