VetGen - The leader in veterinary genetic disease research and genetic disease detection services for purebred animals

Breeds Serviced

    GM1 Gangliosidosis
  • Shiba Inu
  • Siberian Husky
  • GM2 Gangliosidosis
  • Toy Poodle
  • Poodles & all doodles
  • GM2 Gangliosidosis Type 1
  • Japanese Chin


The Gangliosidoses are a group of lysosomal storage diseases which result in improper carbohydrate metabolism. The brain is particularly affected by this, so the major symptoms of all of these diseases are neurological, most notable among these being balance issues, difficulty walking and head tremors. These symptoms are usually noticeable by 3-6 months of age and lead to death in affected animals by about 2 years of age.

These diseases are inherited in an autosomal recessive manner.