- German Shepherd Dogs
RCND -Renal Cystadenocarcinoma Nodular Dermatofibrosis
Renal Cystadenocarcinoma Nodular Dermatofibrosis (RCND) is a naturally occurring canine kidney cancer syndrome that was originally described in German Shepherd dogs.
Autosomal dominant pattern of inheritance:
Only 1 copy of the gene, which may be inherited from either parent, is required to produce the trait. The parent with the dominant trait will pass the affected gene to approximately half its offspring, and the trait will be apparent in both the parent and the affected progeny. Because nodular dermatofibrosis has an autosomal dominant mode of inheritance, all dogs with the defective gene will develop the condition.